What is NAD+
NAD+ is a vital co-enzyme molecule that stands for Nicotinamide Adenine Dinucleotide. Found in every cell of the body, NAD+ is essential for turning nutrients into energy within the mitochondria, cytoplasm and nucleus to correct cellular activity and provide DNA repair. NAD+ helps the body respond to environmental toxins, pro- inflammatory foods, trauma and chronic use of medications.
NAD+ consists of two nucleotides (building blocks of DNA and RNA) joined together by their phosphate groups, making it a dinucleotide. One nucleotide contains nicotinamide and the other has an adenine nucleobase. It’s noted as one of the most important co-factors for improving mitochondrial function.
NAD+ levels decline with age, stress and illness. With countless products on the market and an overload of information, it can be difficult to decipher the best strategies for improving your health. Of all the vitamins and co-enzymes, there’s a reason NAD+ is gaining in popularity. Boosting NAD+ levels aim to bring on powerful healing.
Life-sustaining benefits of NAD+ include:
- Energy Production
- Chromosome Stability
- Longer Telomeres
- Immune-Cell Signaling
- Energy Enzyme Activity
- Improved Neurotransmission
- DNA Repair
- Longevity
How Do Cells Make NAD+
NAD+ mediates multiple major biological processes, is always in high demand, constantly synthesized, metabolized, and recycled in the cell to help it maintain homeostasis. NAD+ is primarily synthesized by liver cells from scratch using multiple dietary sources containing tryptophan like turkey, chicken, salmon, nuts and grains, or vitamin precursors such as nicotinamide. Most tryptophan is metabolized into nicotinamide in the liver where it is released into the serum, taken up by peripheral cells and converted to NAD+.
NAD+ and DNA Repair
An intriguing component of NAD+ is its ability to contribute to DNA repair. Accumulated DNA damage has negative impacts on the aging process and reduces the cell’s ability to repair. Replenishing NAD+ to the cells plays a critical role in mitigating a wide range of health conditions like dementia, diabetes, obesity, addiction and cancer.
It serves as a cofactor for enzymes like sirtuins and poly(ADP-ribose) polymerases (PARPs) that require NAD+ for regulating metabolism, gene expression, cellular health and a longevity mechanism referred to as “Fountains of Youth”.
Brain Health
NAD+ is neurogenerative and found to meet all criteria for a neurotransmitter, the nervous system’s chemical messengers. Qualities of NAD+ include overcoming addiction, trauma, memory loss and cognitive deterioration.
By promoting cellular energy production and supporting DNA repair NAD+ reduces neuroinflammation and enhances synaptic plasticity critical for neuron connections.
Aging and Longevity
Don’t wait until it’s too late. Reduction in NAD+ production is linked to numerous disorders including cognitive decline, metabolic disease, loss of muscle mass and strength, skin conditions and even cancer.
For example, telomeres are DNA structures at the end of chromosomes that protect them from damage and their reduction in length is a marker of cellular aging and predictor of a shortened lifespan. NAD+ is shown to extend telomere length and longevity.
Many diseases have potential to be slowed down or even reversed by restoring NAD+ levels. Studies from the early 1900’s about NAD compliment current studies today showing evidence that NAD+ possesses regenerative properties capable of rebuilding areas in the cells to regulate DNA repair.
NAD+ IV Therapy
NAD+ infusions provide powerful intense healing by delivering the co-enzyme directly into the bloodstream for rapid cellular absorption. NAD+ is administered in varying doses and times depending on the individual’s concern and overall goals whether it be anti-aging, neuro-regenerative, overcoming addiction, weight control, preventative-care or health maintenance. Intuitively your body will use the NAD+ where it’s needed most, generating and clearing cells for each organ to perform its job more effectively.
NAD+ may also be given as an intramuscular injection for optimal health maintenance or implemented daily through supplemental precursors like nicotinamide, a form of the B3 vitamin.
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